Also, the file I downloaded is only 33k in size! It seems that it can not be a correct game rom. I have never heard of such a small file size before. I couldnt find the original SMS file of the game link you provided me so I couldnt verify the correctnesss of the rom file size.
I did try it and it went blank (the sceen) just like if I were to load a .bin file which the DPF doesnt recognize. And from what I remember about the Sega Genesis the Z80 chip in the Genesis model 1 was put in just to make it compatible with the Sega Master System games ( using the power base coverter )so it would depend on the model of the Genesis rather than the backup device given that the backup device recognizes the .smd format. Am I correct in stating this? Perhaps if you know a standard size .sms game that is 512k in size and apply the header to it that may help in narrowing the possibilities down and for once and for all put a rest to this question. And give you a chance to do something else other than answer my long winded questions. Thans again.